System and method for managing routing resources for a measurement task. The system includes a computer and one or more measurement devices. The legs of a route for routing signals in performing the measurement task are created by, for each respective leg: determining if a routing resource for the respective leg is not currently used in an existing route. If not, then the resource is configured with a desired configuration of the respective leg, and a resource reservation indicated, e.g., by incrementing a resource usage count. If the resource is currently used, the desired configuration is compared with the resource's current configuration. If the current configuration conforms to the desired configuration, a resource reservation is indicated, otherwise, an error message indicating that the leg failed is returned, and optionally, an alternative leg for the route is created which includes a different resource than the respective leg. The route is stored.