The present invention is directed to a compound represented by formula
(1): ##STR00001## (wherein R.sup.1 represents an alkyl group which may
have a substituent or an alkenyl group which may have a substituent;
andeach of R.sup.2 and R.sup.3 represents a hydrogen atom, an alkyl
group, a hydroxyalkyl group, a dihydroxyalkyl group, or an alkynyl group,
or R.sup.2 and R.sup.3 form, together with the nitrogen atom adjacent
thereto, a nitrogen-containing saturated heterocyclic group which may
have a substituent) and a drug composition containing the compound. The
compound exhibits tumor necrosis factor (TNF-.alpha.) production
inhibitory effect and improved absorption upon oral administration.