In a multi-panel sunshade device for a vehicle comprising a drive panel and a plurality of follower panels slidably supported between the right and left guide rails to selectively open and close the roof opening, the right and left guide rails each comprises an upper guide rail and a lower guide rail, and right and left front slide shoes of each follower panel are supported by the right and left upper guide rails, respectively, while right and left rear slide shoes of each follower panel are supported by the right and left lower guide rails, respectively. Further, a pair of right and left front slide shoe storing rooms are connected to the right and left upper guide rails, respectively, and a pair of right and left rear slide shoe storing rooms are connected to the right and left lower guide rails, respectively.