The present invention provides compositions and methods for modulating
lymphocyte activation. Nucleic acids encoding proteins and proteins so
encoded which are capable of modulating lymphocyte activation are
provided. Compositions and methods for the treatment of disorders related
to lymphocyte dysfunction or dysregulation are also provided.
Prophylactics and methods for the prevention of such disorders are also
provided. Also provided are compositions and methods for diagnostic and
prognostic determination of such disorders. Further provided are assays
for the identification of bioactive agents capable of modulating
lymphocyte activation.