The present invention concerns a bioactive implant material having a
cartilage-inducing and/or bone-inducing activity composed of two
components A and B, of which A is a bone-inducing and/or
cartilage-inducing protein or protein mixture and preferably one or
several proteins from the TGF-.beta. superfamily, preferably MP52 or a
DNA sequence coding therefor and B is a carrier matrix composed of
calcium phosphate ceramics with an interconnecting microporosity which
already alone has bone-inducing properties. The invention additionally
concerns the production of these compounds and their use for the
treatment of diseases which affect cartilage and/or bones as well as to
treat damage to cartilage and/or bone tissue.