The invention relates to the field of biochemistry, molecular biology,
pharmacology and diagnosis. More specifically the present invention
relates to the production of proteins in a host cell. Even more
specifically, the invention relates to a method for improving expression
of two or more proteins in a (host) cell. The method is suited for
production of, for example, recombinant antibodies that can be used in a
pharmaceutical preparation or as a diagnostic tool. In one embodiment,
the invention provides a method for obtaining a cell which expresses two
or more proteins comprising providing the cell with two or more protein
expression units encoding two or more proteins, characterized in that at
least two of the protein expression units comprise at least one STAR
sequence.