An up-conversion mixing system with high carrier suppression, which includes first and second LPFs to filter a first and a second input signals to thereby produce a first and a second filtered signals respectively; a first amplifier to amplify the first input signal and the first filtered signal to thereby produce a first amplified signal; a second amplifier to amplify the second input signal and the second filtered signal to thereby produce a second amplified signal, wherein the second amplifier is cross-coupled with the first amplifier in order to couple the first and the second amplified signals, thereby reducing a DC offset of a differential voltage output by the first and the second differential output terminals; and a switch to receive a differential local oscillation signal to shift the first and the second amplified signals up to frequencies associated with the local oscillation signal.