A system and method for managing memory resources in a system that allows remote direct access of memory. An aspect of the invention provides for automatically un-binding bound direct-access memory resources based on information received in messages from a remote source. The information may, for example, include a last-segment indicator to indicate that the message segment is the last expected message segment for a message. Another aspect of the invention provides for memory management of directly-accessible sections of memory by assigning a flag to indicate when the section of memory has special access restrictions, such as a set number of allowable accesses. Yet another aspect of the invention provides for a flag to represent when the access restrictions associated with a particular section of memory have been met.