The invention is related to different embodiments of a kit for the
simultaneous qualitative and/or quantitative determination of a multitude
of analytes comprising a sensor platform comprising an optical
thin-film waveguide with a layer (a) transparent at least at an
excitation wavelength on a layer (b) with lower refractive index than
layer (a), also transparent at least at said excitation wavelength, and
at least one grating structure (c) modulated in said layer (a), for the
incoupling of said excitation light into layer (a), at least one array of
biological or biochemical or synthetic recognition elements immobilized
in discrete measurement areas (d) directly or by means of an
adhesion-promoting layer on layer (a), for specific recognition and/or
binding of said analytes and/or for specific interaction with said
analytes, means for laterally resolved referencing of the excitation
light intensity available in the measurement areas, and optionally means
for the calibration of one or more luminescences generated in the
near-field of layer (a) as a consequence of the binding of one or more
analytes or of the specific interaction with one or more analytes,
wherein a liquid sample to be analyzed for said analytes is brought into
contact with said measurement areas on said sensor platform either
directly or after mixture with further reagents. The invention is also
related to analytical systems based on a kit according to the invention
and to methods for the determination of one or more analytes, based on
said kit, and to use thereof.