Systems and methods for multiple input instrumentation buses are disclosed. In one embodiment, a bus assembly includes a control module adapted to be coupled to a network, and a plurality of nodes operatively coupled in a linear topology. A plurality of interface modules are coupled to the nodes. At least one node is adapted to receive a primary response signal from the correspondingly coupled interface module, and a secondary response signal from at least one other node, and to determine which of the primary and secondary response signals arrived first, and to output a corresponding one of the primary and secondary response signals that arrived first.