A system for independent component analysis includes a feedback mechanism based on a plasticity rule, and an electro-kinetic induced particle chain, wherein the feedback mechanism and the electro-kinetic induced particle chain is utilized to extract independent components from a data set or data stream. The electro-kinetic induced particle chain is generally composed of a plurality of interconnected nanoconnections (e.g., nanoparticles) disposed between at least two electrodes in a solution, including for example one or more pre-synaptic electrodes and one or more post-synaptic electrodes. The feedback mechanism generally provides feedback to one or more particles within the electro-kinetic induced particle chain, while the plasticity rule can be non-linear in nature. The feedback mechanism also provides for one or more evaluate phases and one or more feedback phases.