A biofilm resistant fluid handling system is provided having at least one structural component adapted to retain or deliver fluid. The at least one structural component is formed from a biofilm resistant material comprising polymeric resin and an inorganic carrier conjugated with a biocidal metal ion. When a surface of the at least one structural component is exposed to a continuous or intermittent aqueous solution environment the formation of active biofilm on the surface is prevented and planktonic bacteria in proximity of said surface is killed. Additionally, methods for extending the biocidal properties of a biofilm resistant fluid handling system are provided. One includes continuously or periodically introducing a biocidal metal ion into contents of the aqueous solution environment resulting in equilibrium of biocidal metal ion exchange between the biofilm resistant material of the handling system and the aqueous solution environment, Another includes affixing a solvent, comprising an inorganic carrier conjugated with a biocidal metal ion, to the surface of the fluid handling system.