A method and control unit for medication administering devices. The first aspect of the present invention is automatic programming of the scheduled events. The second aspect is simple user-request expression. The third aspect is guided user operation. The forth aspect is automatic medication-storage mapping. The fifth aspect is no clock setting. Prior art systems typically require the user to figure out a loading-scheduling plan, follow the plan to load the medications, program the scheduled events and tell the system how the medications are stored (manual medication-storage mapping). The system of the present invention does the opposite: it figures out the loading-scheduling plan, guides the user to load the medications, program the scheduled events, and establishes medication-storage mapping, all automatically. The system of the present invention is extremely easy to use, and vision-impaired users can easily use it.