An order evaluation system for use in a healthcare location evaluates an order against a first set of patient assessment data elements to determine whether the order should be issued. If the order is issued, a rules generator generates a patient-specific rule that is consistent with the order. The patient-specific rule is continuously applied to a second set of patient assessment data to determine whether the rule has been contravened. If the rule is contravened, an alert is issued. An alert may direct changes in, or cancellation of, an order.