Described are determination procedures for fibrinogen and/or
fibrinogen-derivatives by matrix-independent turbidimetry. In the FIFTA
called procedure the fibrinogen activity is preferably determined in an
undiluted sample by addition of thrombin and/or albumin, as well as
polybrene if appropriate, in PBS and determination of the increase in
absorbance at 405 nm. In the FIATA called procedure the
fibrinogen-concentration and/or the concentration of
fibrinogen-derivatives is preferably determined by addition of vancomycin
and determination of the increase in turbidity at 405 nm. It is
standardized by usage of plasma standards of known fibrinogen-activity
and/or fibrinogen-concentration.