The present invention relates to a production process of polyphenylene ether composition comprising (A-1) a polyphenylene ether, (A-2) a polystyrene, (A-3) an ester phosphate, (B) a hindered amine light stabilizer, and (C) an ultraviolet absorber. The feature of the present invention is melt compounding a part of raw materials to obtain a pre-mixture at Step 1, and melt compounding the pre-mixture and the rest of the raw materials at Step 2. A polyphenylene ether composition which has a good light-discoloration resistance and causes little unmelted portion, and to a molded article formed from the polyphenylene ether composition can be obtained according to the production process of the present invention.