The present claimed invention intends to provide a responsive glass membrane for ion selective electrode glass and an ion selective electrode comprising the responsive glass membrane that produces a self-cleaning function when the ultraviolet rays are irradiated although no change is brought in a composition of a sample solution as being an object to be measured and that is low in electric resistance value and superior in responsivity under an ordinary measurement environment.The responsive glass membrane for ion selective electrode is made of the titanium-containing oxide glass that contains 20.about.80 mol % of titanium dioxide and lithium oxide.