The present invention provides a benzimidazole compound represented by
Formula (I)
##STR00001##
wherein X.sup.1 is oxygen or carbonyl, and R.sup.1 is a furan ring having
1 to 3 substituents or a pyrrole ring that may have 1 to 3 substituents;
excluding compounds represented by Formula (I) wherein at least one of
the substituents is a phosphoric acid group or a phosphoric ester group;
or a salt thereof. The benzimidazole compound or salt thereof has
excellent prostaglandin synthase inhibitory activity, and is useful as an
agent for preventing and/or treating diseases in which prostaglandin D2
or metabolites thereof participates, such as allergic and inflammatory
diseases, and as inhibitor for the exacerbation of Alzheimer's disease or
cerebral damage.