Compounds of Formula (I) that act as antagonists at the mu, kappa and/or delta opioid receptors and therefore useful in the treatment of diseases, conditions and/or disorders that benefit from such antagonism in animals are described herein. ##STR00001## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are described herein.

 
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< Derivatives of 4,5-diarylpyrrole, preparation method thereof and use of same in therapeutics

> Methods for concomitant administration of colchicine and macrolide antibiotics

> Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one useful in the preparation of the DPP-IV inhibitor (S)-1 ((2S,3S,11bS)-2-amino-9,10-dimethoxy-1,3,4,6,7, 11b-hexahydro-2H-pyrido[2,1-a] isoquinolin-3-yl)-4-fluoromethyl-pyrrolidin-2-one
~ 00560