A fuel cell having a stack structure is provided. The fuel cell includes plural unit cells each of which includes an anode and a cathode which are provided on both sides of a predetermined electrolyte membrane, and a catalytic layer which is provided in at least one of the anode and the cathode, and which supports a catalyst for promoting an anode reaction or a cathode reaction, the plural unit cells being stacked to form a stack structure. In the fuel cell, the plural unit cells include a unit cell including a catalyst layer supporting a catalyst which is different from catalysts supported by catalyst layers of other unit cells in at least one of type, weight, and specific surface area.