The exemplary embodiment disclosed herein comprises several aspects of defining and using optimal color test patches for calibrating a printing system for various purposes (e.g., multi-media, gamut extension, drifting correction, etc.). One aspect is the creation and use of color patches where the color patches are selected optimally to result in minimum mean square error when those color patches are used to determine weights of a limited number of basis vectors that model the system (e.g., model the print engine response). A joint optimization technique is given as a method to select the optimal color test patches for calibration.