An automated analyzer for performing multiple diagnostic assays
simultaneously includes multiple stations, or modules, in which discrete
aspects of the assay are performed on fluid samples contained in reaction
receptacles. The analyzer includes stations for automatically preparing a
specimen sample, incubating the sample at prescribed temperatures for
prescribed periods, preforming an analyte isolation procedure, and
ascertaining the presence of a target analyte. An automated receptacle
transporting system moves the reaction receptacles from one station to
the next. The analyzer further includes devices for carrying a plurality
of specimen tubes and disposable pipette tips in a machine-accessible
manner, a device for agitating containers of target capture reagents
comprising suspensions of solid support material and for presenting the
containers for machine access thereto, and a device for holding
containers of reagents in a temperature controlled environment and
presenting the containers for machine access thereto. A method for
performing an automated diagnostic assay includes an automated process
for isolating and amplifying a target analyte. The process is performed
by automatically moving each of a plurality of reaction receptacles
containing a solid support material and a fluid sample between stations
for incubating the contents of the reaction receptacle and for separating
the target analyte bound to the solid support from the fluid sample. An
amplification reagent is added to the separated analyte after the analyte
separation step and before a final incubation step.