In a dispensing system for dispensing wet wipes, a wet wipe has an aqueous solution and microencapsulated delivery vehicles including a temperature agent, and is disposed in a wet wipe container. A cartridge is held in assembly with the wet wipe container and has an activating device that facilitates rupturing of the microencapsulated delivery vehicles as the wet wipe is removed from the dispensing system to allow contact between the temperature change agent and the aqueous solution of the wet wipe to thereby dispense a warm or cooled wet wipe. In another embodiment, the wet wipe has an aqueous solution and a lotion having the microencapsulated heat delivery vehicles disposed in the cartridge free from contact with the wet wipe. The cartridge also has an applicator that is operable to apply the lotion to the wet wipe as the wet wipe is removed from the wet wipe container.