One aspect of the invention provides an analyte monitor including a
sensing volume, an analyte extraction area in contact with the sensing
volume adapted to extract an analyte into the sensing volume, and an
analyte sensor adapted to detect a concentration of analyte in the
sensing volume. The sensing volume is defined by a first face, a second
face opposite to the first face, and a thickness equal to the distance
between the two faces. The surface area of the first face is about equal
to the surface area of the second face and the extraction area is about
equal to the surface area of the first and second face of the sensing
volume. The analyte sensor includes a working electrode in contact with
the sensing volume, the working electrode having a surface area at least
as large as the analyte extraction area, and a second electrode in fluid
communication with the sensing volume.