An inbred maize line, designated HLA22ND, is disclosed. The invention relates to the seeds of inbred maize line HLA22ND, to the plants of inbred maize line HLA22ND and to methods for producing a maize plant, either inbred or hybrid, by crossing the inbred line HLA22ND with itself or another maize line. The invention further relates to methods for producing a maize plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred maize lines derived from the inbred HLA22ND.