An electrophoretic display panel with a fast response speed and its fabrication method are disclosed. The electrophoretic display panel includes a first array substrate including a gate line and a data line extending perpendicularly to each other, a thin film transistor connected to the gate line and the data line, and a pixel electrode electrically connected to the thin film transistor. The electrophoretic display panel also includes a second array substrate coupled the first array substrate and including a common electrode capable of forming an electric field with the pixel electrode, a spacer formed on at least one of the first array substrate or the second array substrate to define a charging region in the pixel region; and an electrophoretic medium in the charging region between the first and second array substrates.