The present invention relates to antibody molecules, in particular
antibody molecules that bind Transforming Growth Factor beta (TGF.beta.),
and uses thereof. More particularly, the invention relates to antibody
molecules that bind and preferably neutralize TGF.beta.1, TGF.beta.2 and
TGF.beta.3, so-called "pan-specific" antibody molecules, and uses of such
antibody molecules. Preferred embodiments within the present invention
are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or
IgG4) or antibody fragments (e.g. scFv, Fab, dAb).