The present invention relates to taxane analogs for the treatment of
cancer having the general formula: ##STR00001## wherein R.sub.1 and
R.sub.2 are each selected from H, an alkyl group, an olefinic group, an
aromatic group, an O-alkyl group, an O-olefinic group, or an O-aromatic
group; R.sub.3 is hydroxyl or OP.sub.1; R.sub.4 and R.sub.5 are each
hydroxyl or R.sub.7COO; R.sub.6 is hydroxyl, OP.sub.2, R.sub.7COO, or an
ether functionality; R.sub.7 is an alkyl group, an olefinic group, or an
aromatic group; P.sub.1 and P.sub.2 are each hydroxyl protecting groups;
R.sub.8 and R.sub.9 are each selected from H, alkyl group, olefinic or
aromatic group. The present invention is also directed to production
methods and intermediates useful in the formation of these new taxane
analogs. The methods may begin with a starting compound, such as
paclitaxel or docetaxel, which is converted into a taxane analog through
various intermediate compounds.