The technical problem underlying the present invention is to provide peptides corresponding to immunologically important epitopes on bacterial and viral proteins, as well as the use of said peptides in diagnostic or immunogenic compositions. The invention relates to a process for the in vitro determination of antibodies, wherein the peptides used are biotinylated, particularly in the form of complexes of streptavidin-biotinylated peptides or of avidin-biotinylated peptides.

Het technische probleem die aan de onderhavige uitvinding ten grondslag liggen is peptides aan immunologisch belangrijke epitopes op bacteriële en virale proteïnen beantwoorden, evenals het gebruik die van bovengenoemde peptides in kenmerkende of immunogene samenstellingen te verstrekken. De uitvinding heeft op een proces voor de bepaling in vitro van antilichamen betrekking, waarin gebruikt peptides biotinylated zijn, in het bijzonder in de vorm van complexen van streptavidin-biotinylated peptides of van avidin-biotinylated peptides.

 
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