A method for identifying a protein antigen to a target fungus is disclosed.
The method comprises screening expressed proteins from a cDNA gene
expression library with antisera to the target fungus and cross-screening
with antisera to a nontarget fungus. Antibodies to the protein antigen are
also disclosed. Methods for detecting the presence or absence of the
antibodies or of the protein antigen are also disclosed, as well as kits
for performing such assays. In preferred embodiments, the target fungus is
H. capsulatum.
