Synergistic immixtures of ascorbic acid with at least one monosaccharide
ester of ascorbic acid and/or at least one metal salt of phosphorylated
ascorbic acid more effectively increase the synthesis of epidermal
ceramides in human skin, especially types IV to VII ceramides, as well as
improve the barrier function, moisture content and/or suppleness/surface
appearance of the skin and which otherwise combat/prevent intrinsic aging
thereof and are useful for the treatment of dermatitis.