This invention provides processes for the preparation of compounds having
the structure: 1
wherein
X and Y are same or different, and H, OH, OR, SH, SR, NH.sub.2, NHR', or
NR'R"
Z is H, F, Cl, Br, I, CN, or NH.sub.2.
R is hydrogen, halogen, lower alkyl of C.sub.1-C.sub.6 or aralkyl,
NO.sub.2, NH.sub.2, NHR', NR'R", OH, OR, SH, SR, CN, CONH.sub.2,
CSNH.sub.2, CO.sub.2H, CO.sub.2R', CH.sub.2CO.sub.2H, CH.sub.2CO.sub.2R',
CH.dbd.CHR, CH.sub.2CH.dbd.CHR, or C.dbd.CR.
R' and R" are same or different, and lower alkyl of C.sub.1-C.sub.6.
R.sup.13 is hydrogen, alkyl, acyl, phosphate (monophosphate, diphosphate,
triphosphate, or stabilized phosphate) or silyl; and