This invention relates to compounds, compositions, and methods useful for
modulating chemokine receptor (CXCR) gene expression using short
interfering nucleic acid (siNA) molecules. This invention also relates to
compounds, compositions, and methods useful for modulating the expression
and activity of other genes involved in pathways of CXCR gene expression
and/or activity by RNA interference (RNAi) using small nucleic acid
molecules. In particular, the instant invention features small nucleic
acid molecules, such as short interfering nucleic acid (siNA), short
interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA),
and short hairpin RNA (shRNA) molecules and methods used to modulate the
expression of CXCR genes such as CXCR4 and CXCR7A.
