This invention relates to compounds, compositions, and methods useful for
modulating TRPM7 gene expression using short interfering nucleic acid
(siNA) molecules. This invention also relates to compounds, compositions,
and methods useful for modulating the expression and activity of other
genes involved in pathways of TRPM7 gene expression and/or activity by
RNA interference (RNAi) using small nucleic acid molecules. In
particular, the instant invention features small nucleic acid molecules,
such as short interfering nucleic acid (siNA), short interfering RNA
(siRNA), double-stranded RNA (dsRNA), micro-RNA (mRNA), and short hairpin
RNA (shRNA) molecules and methods used to modulate the expression of
TRPM7 genes.