Devices, methods, and improved formulation for transmucosal vaginal delivery
of bisphosphonates. A targeted site delivery of bisphosphonates to the systemic
circulation using a vaginal device comprising an improved bisphosphonate formulation
for transmucosal delivery. A method for treatment of osteoporosis and related bone
and skeleton diseases, for prevention of bone breakdown and loss of bone mass and
strength by intravaginal administration of bisphosphonates to the vagina and transmucosal
delivery of bisphosphonates to the general circulation.
