Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect

   
   

Partially desulphated glycosaminoglycan derivatives are described, particularly heparin, and more particularly formula (I) compounds where the U, R and R.sub.1 groups have the meanings indicated in the description. Said glycosaminoglycan derivatives are endowed with antiangiogenic and heparanase-inhibiting activity ans are devoid of anticoagulant activity.

 
Web www.patentalert.com

< New COMT inhibitors for the treatment of depression and impaired cognition

< Modified hyaluronic acid for use in musculoskeletal tissue repair

> IL-23p40 specific immunoglobulin derived proteins, compositions, methods and uses

> Process for obtaining transgenic plants which have improved capacity for the uptake of nutrients and tolerance to toxic compounds which are present in the soil

~ 00189