An isolated acid having the sequence of a) SEQ ID NO: 1; b) the sequence
of SEQ ID NO: 2; c) the sequence of SEQ ID NO: 3; d) a sequence
complementary to any of a), b), or c); or e) a sequence of at least 10
contiguous nucleotides specific for any of a)-d). The invention relates
to the identification and characterization of a hitherto unidentified
human gene, hGC-1. The protein encoded by hGC-1 appears to be a member of
the olfactomedin-related proteins. The invention relates generally to the
gene (hGC-1), nucleic acids, cDNA, vectors, polypeptides, protein,
antibodies, cells, transgenic animal, and other compositions related to
hGC-1. Additionally, primers are provided for identifying hGC-1. The
invention further relates to methods of using these compositions, such as
diagnosis and treatment of various cancers, and kits comprising these
compositions.