Compounds of formula I ##STR00001## as well as pharmaceutically acceptable salts and esters thereof, wherein R.sup.1, R.sup.2, R.sup.3, A.sup.1 and A.sup.2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.

 
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> 4-hydroxymethyl-1-aryl-cyclohexylamine compounds

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