In its many embodiments, the present invention provides tricyclic
compounds of formula I (wherein J.sub.1-J.sup.3, X, Z, and R.sup.1,
R.sup.3, and R.sup.4 are as defined herein) useful as metabotropic
glutamate receptor (mGluR) antagonists, particularly as selective
metabotropic glutamate receptor 1 antagonists, pharmaceutical
compositions containing the compounds, and methods of treatment using the
compounds and compositions to treat diseases associated with metabotropic
glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine,
anxiety, urinary incontinence and neurodegenerative diseases such
Alzheimer's disease.