In its many embodiments, the present invention provides tricyclic
compounds of formula I (wherein J.sup.1-J.sup.3, X, Z, and
R.sup.1-R.sup.4 are as defined herein) useful as metabotropic glutamate
receptor (mGluR) antagonists, particularly as selective metabotropic
glutamate receptor 1 antagonists, pharmaceutical compositions containing
the compounds, and methods of treatment using the compounds and
compositions to treat diseases associated with metabotropic glutamate
receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety,
urinary incontinence and neurodegenerative diseases such Alzheimer's
disease.