A pillbox that can be used with a portable electronic device ("PED") such as a cellular telephone or personal digital assistant includes a generally cubic body portion that is attached to one end of a PED. The body portion defines a compartment within which medication can be placed. Preferably, an extension projects from one wall of the body portion and the extension is connected to the PED. The body portion preferably conforms generally to the contour of the PED. A door is connected to the body portion to permit selective access to the compartment. Other embodiments of the invention include a holster within which the PED can be inserted. In some of the embodiments, the door defines the medication-storage compartment.