An optical waveguide feedthrough assembly passes at least one optical waveguide through a bulk head, a sensor wall, or other feedthrough member. The optical waveguide feedthrough assembly comprises a cane-based optical waveguide that forms a glass plug sealingly disposed in a feedthrough housing. A seal fills an annular space between the glass plug and the housing. The seal may be energized by a fluid pressure in the housing to establish sealing engagement. Further, the seal may provide bidirectional sealing. The feedthrough assembly is operable in high temperature and high pressure environments.